Book your Houston hotel stay at Houston Marriott Medical Center / Museum District, ideally located four miles from downtown and six miles from the Galleria. Located next to Methodist Hospital, our hotel in Houston, TX, is connected to the Texas Medical Center via skybridge. Enjoy a complimentary shuttle within two miles to destinations such as: Museum District, Rice Village, Rice University, MD Anderson and TMC facilities. Take the METRORail red line in front of the hotel to events at NRG Park or downtown Houston. Enjoy casual cuisine in Main & Green or relax for happy hour, craft cocktails and dinner in CURATE. Upgrade your stay to gain exclusive access to our M Club lounge. Our Houston hotel boasts a newly renovated lobby, 24-hour fitness center, and refreshed event space, perfect for meetings, galas and weddings. Relax in a spacious guest room and hotel suites with premium bedding, Smart TVs, and refrigerators, perfect for long-term stays in Houston, Texas.