The brand-new Odessa Marriott Hotel & Conference Center is poised to become the new focal point of Downtown Odessa. Inspired by the rich oil and mineral history and taking a cue from the Odessan landscape, the interior design combines natural woods with elegant stone elements creating a dramatic and sophisticated look. This Ruggedly refined Hotel is a stylish modern Western dreamscape offering world-class accommodations and an expansive conference center built for discerning business and leisure travelers alike. Those “In The Know” see Odessa as one of the fastest growing cities in Texas and is located in the heart of the oil country. It is home to The University Of Texas Permian Basin and Odessa College as well as the Odessa Regional Medical Center and the Medical Center Health System. Our city is unique in the amenities and customer service it provides to our West Texas visitors. Odessa perfectly blends corporate, healthcare and energy with the ambiance of a small town and BIG Texas Hospitality.